Twelve hour reproducibility of choroidal blood flow parameters in healthy subjects

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Twelve hour reproducibility of choroidal blood flow parameters in healthy subjects.

AIMS/BACKGROUND To investigate the reproducibility and potential diurnal variation of choroidal blood flow parameters in healthy subjects over a period of 12 hours. METHODS The choroidal blood flow parameters of 16 healthy non-smoking subjects were measured at five time points during the day (8:00, 11:00, 14:00, 17:00, and 20:00). Outcome parameters were pulsatile ocular blood flow as assesse...

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Alterations of Choroidal Blood Flow Regulation in Young Healthy Subjects with Complement Factor H Polymorphism

A common polymorphism in the complement factor H gene (rs1061170, Y402H) is associated with a high risk of age-related macular degeneration (AMD). In the present study we hypothesized that healthy young subjects homozygous for the high-risk haplotype (CC) show abnormal choroidal blood flow (ChBF) regulation decades before potentially developing the disease. A total of 100 healthy young subjects...

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Retinal blood flow in healthy young subjects.

PURPOSE To characterize total retinal blood flow in a group of healthy subjects. METHODS Included in this study were 64 healthy volunteers. Retinal venous diameters were measured using a dynamic vessel analyzer. Retinal blood velocities were measured using bidirectional laser Doppler velocimetry. All vessels with a diameter of >60 μm entering the optic nerve head were measured. Total retinal ...

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Choroidal Thickness in Healthy Subjects

Purpose To measure the choroidal thickness by enhanced depth imaging optical coherence tomography (EDI-OCT) in normal eyes. Methods In a prospective case series, 208 eyes of 104 normal Iranian subjects were enrolled. Complete ophthalmic examination was performed. Inclusion criteria were best corrected visual acuity (BCVA) ≥20/20, ≤ ±1 diopter of refractive error in either spherical or cylindr...

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PURPOSE To characterize the role of the endothelin system in the blood flow control of the optic nerve head and of the choroid in humans. METHODS Two studies were performed in healthy subjects. Study 1 was a randomized, placebo-controlled, double-masked, balanced, two-way crossover design and study 2 a three way-way crossover design. In study 1 twelve healthy male subjects received endothelin...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 2004

ISSN: 0007-1161

DOI: 10.1136/bjo.2003.028480